Last Updated: Tuesday, June 11, 2013
Principal Investigator: Jeremy M. Veenstra-VanderWeele, M.D.
Other researchers: Kevin Sanders, MD
The purpose of the study is to find out if the investigational drug called metformin is safe and helpful in reducing weight gain for patients with an autism spectrum disorder who are taking anti-psychotic medication. Metformin is already used safely in adults and children with diabetes.
Evaluations, study visits, and study drug are provided at no cost.
A blood draw is required at 3 separate visits.
Every participant will be given the opportunity to receive study medication.
This study is sponsored by The Autism Intervention Research Network on Physical Health as part of the Autism Treatment Network.
Children age 6– 17 with an autism spectrum disorder who are taking an atypical antipsychotic like Risperidone (risperidol), Zyprexa (Olanzapine) and have gained unwanted weight.
Evaluations, study visits, and study drug are provided at no cost. At least $35/visit to the family.
12 visits to Vanderbilt University in Nashville, TN.
Adolescents (12-17 years old) with Fragile X syndromeCompensation: Yes
Children with a confirmed diagnosis of Fragile X between 3 and 11 years.Compensation: Yes
Adults age 14– 50 with Fragile X for a study using an investigational drug.Compensation: Yes
People with Fragile X age 5-13Compensation: Yes
Children age 6-18 with autism spectrum disorders with and without GI problems.Compensation: Yes
Males ages 18-45 with diagnosis of autism spectrum disorder. Must be verbal.Compensation: Yes
Visit this investigator's people page to list all of their studies together.