Vanderbilt Kennedy Center

Brain Imaging Study of Adults with Down Syndrome

Last Updated: Friday, January 25, 2013

Principal Investigator: Tricia Thornton-Wells, Ph.D.

Other researchers: Tracy McGregor, MD William Petrie, MD


Alzheimer Disease is far more common in adults with Down Syndrome, but not every person with Down Syndrome will get Alzheimer Disease. Our study wants to find out more about the development of Alzheimer Disease in people with Down Syndrome, and you can help!

We ask parents/caregivers to answer questions:

  • About the adult’s daily functioning
  • About signs of dementia

We ask the adult with Down Syndrome to:

  • Play memory games
  • Let us take pictures of his/her brain using MRI
  • Provide a DNA sample
  • Get compensated for his/her time ($20 per hour)

Participation in the study will require 1 to 3 trips to Vanderbilt University in Nashville, TN. We'd like to see you every year for 3 years. The study will take approximately 8 hours total, which can be spaced out over 2 or 3 days, at your convenience.

If you choose to complete a release form, we can provide to your healthcare provider a copy of the cognitive testing results and/or the structural MRI scan.

Participant Criteria

Adults with Down syndrome between 30 and 75 years old


$20/hour for study tasks.

Visit Requirements

1 to 3 trips to Vanderbilt University in Nashville, TN.


Download Brochure

Contact Information

Genea Crockett

Want to Participate in this Study?

Enter your name and contact information and this study's coordinators will contact you if there are openings available.