Instructor of Medicine
7465 MRB IV
Dr. Pendergast's broad research interest is to understand how the circadian system in mammals responds to environmental cues to coordinate behavior and physiology and how disruption of this process results in poor health. During her postdoctoral tenure, she received training in all aspects of chronobiology, including behavioral and physiological assays and real-time measurements of circadian gene expression in adult brain slices and peripheral tissues. Her research has focused not only on studies of the fundamental aspects of circadian rhythms, such as temperature compensation and entrainment, but also on studies with translational impact, such as those of feeding behavior and metabolic physiology. Dr. Pendergast has also investigated circadian rhythms in Fragile X mice and in mice treated with the potent teratogenic dioxin, TCDD.