Assistant Professor of Pediatrics, Division of Genetic and Genomic Medicine; Director, Down Syndrome Clinic
Tracy McGregor's current research deals with the genetic etiologies of birth defects. She and colleagues are working to elucidate genetic copy number variations that account for the relatively high incidence of congenital heart defects. In her own work, she is examining the role of lysyl oxidases in the development of idiopathic scoliosis. It is her intent to correlate genetic polymorphisms and mutations in the lysyl oxidase genes with the development of adolescent idiopathic scoliosis.
McGregor recently accepted the role of Medical Director of the Vanderbilt Down Syndrome Clinic, and in this role, she collaborates with Vanderbilt Kennedy Center researchers in studies regarding the impact of congenital heart disease in this population of patients. She plans to work extensively with researchers within the VKC and in the Vanderbilt Medical Center to promote further investigation into Down syndrome through the development of a research registry of Down syndrome patients. This repository will contain medical as well as social information that will be linked to DNA samples that can be used for future studies. McGregor is also working with collaborators at Vanderbilt and other institutions to develop accurate and electronically available Down syndrome growth charts to aid in the medical care of this patient population.