Genetics is a conceptually broad term referring both to the science of heredity and the biological process of transmission of characteristics from progenitor to offspring.
Genetic analysis of midline cell fate specification--National Institute of Child Health and Human Development (1999-2004)
Bruce Appel, Ph.D., Principal Investigator
Project 4: Neurogenomic model for dopamine transporter regulation--National Institute of Diabetes and Digestive and Kidney Diseases (2000-2005)
Randy Blakely, Ph.D., Principal Investigator
Neurological function of fragile x gene in the drosophila genetic model system--National Institute of Child Health and Human Development (2001-2006)
Kendal Broadie, Ph.D., Principal Investigator
This study is aimed at uncovering the synaptic defects of fragile X syndrome, and identifying and characterizing novel FMR1 interacting genes in Drosophila
Genetic analysis of synapse formation and function--National Institute of General Medical Sciences (1997-2006)
Kendal Broadie, Ph.D., Principal Investigator
This project focuses on the functional development of the glutamatergic synapse, using a forward genetic approach at the Drosophila neuromuscular junction
Regulation of RNA editing in the CNS--National Institute of Neurological Disorders and Stroke (1995-2004)
Ronald Emeson, Ph.D., Principal Investigator
The major goal of these studies are (1) to define the cis-active elements and trans-acting factors responsible for mediating the editing of RNA transcripts encoding the double-stranded RNA-specific adenosine deaminase, ADAR2; (2) to examine the role of ADAR protein levels in the regulation of ADAR substrate specificity; and (3) to examine the molecular and phenotypic consequences of ADAR2 misregulation in genetically modified strains of mice.
Hereditary defects in human sodium channels--National Institute of Neurological Disorders and Stroke (1994-2006)
Alfred George, Jr., M.D., Principal Investigator
The goal of this project is to functionally characterize mutations that occur in human sodium channels in inherited epilepsy syndrome.
Fetal cocaine and gene expression defects in forebrain--National Institute on Drug Abuse (2000-2004)
Pat Levitt, Ph.D., Principal Investigator, Gregg Stanwood
Project 2: Gene expression patterns in prefrontal cortical injury--National Institute of Mental Health (1990-2003)
Pat Levitt, Ph.D., Principal Investigator
Molecular physiology of circadian pacemaking--National Institute of Mental Health (2001-2006)
Douglas McMahon, Ph.D., Principal Investigator
This project examines the links between gene expression and physiology in the brain’s biological clock.
Gene discovery in a putative mouse model of ADHD--National Institute of Neurological Disorders and Stroke (2003-2004)
Michael McDonald, Ph.D., Principal Investigator
GH alternative splicing: Mechanisms and disease--National Institute of Diabetes and Digestive and Kidney Diseases (1994-2005)
John Phillips, M.D., Principal Investigator
Chromosome
Disorders , Family Village Library
Human
Genome Project Information: Links to the Genetic
World
Tennessee Consortium for Mouse Functional Genetics
National Center for Biotechnology Information: Online Mendelian Inheritance in Man